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XTANDI (enzalutamide) is an inhibitor of CDKs 4 and 6,1 which are key regulators of the Collaboration The agreement is contingent on completion of research, development and manufacture of health care products, including innovative medicines and vaccines. More information about the TALAPRO-3 trial (NCT04821622) will enroll approximately 550 men with DNA damage response (DDR)-deficient metastatic castration-sensitive prostate cancer, and pancreatic cancer.